| 货号 | 39570 |
| 同种亚型 | Serum |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Western Blot/Immunoprecipitation |
| 使用方法 | Validated Applications: IP: 10 µl per IP WB: 1:500 - 1:2,000 dilution |
| 供应商 | Active Motif |
| 纯化方式 | None |
| 免疫原 | This L3MBTL2 antibody was raised against a His-tagged fusion protein containing amino acids 1-230 of human L3MBTL2. |
| 背景 | L3MBTL2 (Lethal (3) malignant brain tumor-like 2 protein) is a putative member of the polycomb group family and is the human homolog of Drosophila Sfmbt, critical for Hox gene silencing. L3MBTL2 contains one FCS-type zinc finger and four MBT (malignant brain tumor) repeats. L3MBTL2 associates with chromatin-remodeling complexes and helps inhibit the expression of proteins that trigger the cells into mitosis. L3MBTL2 is a part of a complex involved in the G0 phase of the cell cycle. This complex contains other proteins such as E2F-6, Max or HP1 gamma, and participates in transcriptional repression. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Rabbit serum containing 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 90 kDa |
| 参考文献 |
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L3MBTL2 antibody (pAb) tested by Immunoprecipitation. 10 µl of L3MBTL2 antibody was used to immunoprecipitate L3MBTL2 from 500 µg of HeLa nuclear cell extract (lane 2). 10 µl of rabbit IgG was used as a negative control (lane 1). The immunoprecipitated protein was detected by Western blotting using the L3MBTL2 antibody at a dilution of 1:2,000. | |
L3MBTL2 pAb tested by Western blot. Detection of L3MBTL2 by Western blot analysis with 20 µg HeLa nuclear extract and a 1:2,000 dilution of L3MBTL2 pAb. |
