| 货号 | 39362 |
| 同种亚型 | IgG |
| 反应种属 | Human, Other (Wide Range) |
| 来源宿主 | Rabbit |
| 应用 | Western Blot |
| 使用方法 | Validated Applications: WB: 1:250 - 1:1,000 dilution |
| 供应商 | Active Motif |
| 纯化方式 | Affinity Purified |
| 免疫原 | This MRG15 antibody was raised against a peptide corresponding to the C-terminus of human MRG15. |
| 背景 | MRG15 (MORF4-Related Gene on chromosome 15) is the homolog of the yeast Eaf3 protein and belongs to the MRG family of genes, which are involved in various cellular processes as cellular aging, positive and negative transcriptional regulation and DNA damage repair. MRG15 can be associated with both histone deacetylase and histone acetyltransferase complexes (such as the NuA4 histone acetyltransferase complex, which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal Histone H2A and Histone H4). MRG15, thus, potentially plays a role in both transcriptional silencing and activation. In addition to the more conserved MRG motifs, MRG15 also contains a chromodomain near the N-terminus. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 39 kDa |
| 参考文献 |
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MRG15 pAb tested by Western blot. Nuclear extract of HeLa cells (20 µg) was probed with MRG15 pAb (1:500 dilution). |
