| 货号 | 39195 |
| 同种亚型 | IgG |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | Immunofluorescence/Immunocytochemistry |
| 使用方法 | Validated Applications: ICC/IF: 1 - 5 µg/ml dilution Published Applications: see references |
| 供应商 | Active Motif |
| 纯化方式 | Protein A Chromatography |
| 免疫原 | This Rad51 antibody was raised against full-length human Rad51 expressed in E. coli. |
| 背景 | Rad51(BRCC5,RecA) is known to be involved in the homologous recombination and repair of DNA. Rad51 can interact with the ssDNA-binding protein RPA and Rad52, and it is thought to play roles in homologous pairing and strand transfer of DNA. Rad51 is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | PBS pH 7.5 containing 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 37 kDa |
| 参考文献 |
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Rad51 pAb tested by immunofluorescence. HEK293 cells stained with Rad51 polyclonal antibody (green) and DAPI (blue). |
