货号 | 39102 |
同种亚型 | Serum |
反应种属 | Human |
来源宿主 | Rabbit |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1:500 - 1:2,000 dilution Published Applications: WB See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | None |
免疫原 | This Copine I antibody was raised against a peptide corresponding to amino acids 519-532 of human Copine I. |
背景 | Copine I (CPNE1) is a member of a family of calcium phospholipid-binding proteins that play a role in cell signaling. Copine I augments the activated Tumor Necrosis Factor-alpha (TNF-α) signaling pathway in a calcium-dependent manner. Copine I is a repressor protein that physically interacts with NFκB p65 to inhibit NFκB-mediated transcription. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Rabbit serum containing 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 68 kDa |
参考文献 |
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Copine I pAb tested by Western blot. Detection of Copine I by Western blot analysis. 20 µg of PC-3 whole-cell extract probed with Copine I pAb at a 1:2,000 dilution. |