| 货号 | 61232 |
| 克隆类别 | BCL11A/123 |
| 同种亚型 | IgG1 |
| 反应种属 | Human |
| 来源宿主 | Mouse |
| 应用 | Western Blot/Immunofluorescence/Immunohistochemistry/Immunocytochemistry |
| 使用方法 | Published Applications: ICC/IF IHC WB See references for more information. Individual optimization may be required. |
| 供应商 | Active Motif |
| 纯化方式 | Protein G Chromatography |
| 免疫原 | This BCL11A antibody was raised against a recombinant protein corresponding to amino acids 637-835 of BCL11A-XL (B-cell lymphoma/leukemia 11A extra long form). |
| 背景 | BCL11A(B-cell CLL/lymphoma 11A) is a transcriptional regulator, a myeloid and B-cell proto-oncogene and plays important roles in leukemogenesis and hematopoiesis. BCL11A is involved in regulating hemoglobin gene expression. BCL11A regulates hemoglobin gene switching during fetal development and silencing of γ-globin expression in adults. BCL11A interacts with the Mi-2/NuRD chromatin remodeling complexes, as well as the erythroid transcription factors GATA1 and FOG1. Abundant expression of full-length forms of BCL11A is developmentally restricted to adult erythroid cells. |
| 运输条件 | Blue Ice |
| 存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
| 存储溶液 | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
| 计算分子量 | 100kD |
| 参考文献 |
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