货号 | 39768 |
克隆类别 | CO1531 |
同种亚型 | IgG2a |
反应种属 | Human |
来源宿主 | Mouse |
应用 | Western Blot/Immunoprecipitation/Immunohistochemistry |
使用方法 | Published Applications: IP WB IHC See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This Estrogen Receptor beta antibody was raised against a recombinant protein corresponding to amino acids 212-477 of human Estrogen Receptor beta. |
背景 | ERβ(estrogen receptor β) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding and activation of transcription. ERβ localizes to the nucleus where it may form a homodimer or a heterodimer with ER alpha. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer and osteoporosis. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 59 kDa |
参考文献 |
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