货号 | 39696 |
克隆类别 | 3F2/4 |
同种亚型 | IgG |
反应种属 | Human, Mouse |
来源宿主 | Mouse |
应用 | Western Blot |
使用方法 | Validated Applications: WB: 1 - 2 µg/ml dilution |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This Mi-2 beta antibody was raised against a synthetic peptide derived from human Mi-2B. |
背景 | Mi-2β(Mi-2beta,CHD4,chromodomain helicase DNA-binding protein 4) represents the major Mi-2 isoform present in the complex Mi-2/NuRD. This complex is a multi-subunit protein complex containing both histone deacetylase and nucleosome-dependent ATPase subunits. Current models predict that this complex functions primarily in transcriptional repression. In addition to the ATPase domain, Mi-2 beta contains a chromodomain and two PHD domains. Mi-2 beta interacts with BRG-1, a component of the SWI/SNF complex, and the RET finger protein (RFP). |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 240 kDa |
参考文献 |
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Mi-2 beta pAb tested by Western blot. Nuclear extract of Jurkat cells stained with Mi-2 beta mAb at a dilution of 2 µg/ml. |