货号 | 39678 |
同种亚型 | IgG |
反应种属 | Human |
来源宿主 | Mouse |
应用 | Western Blot/Immunoprecipitation/Immunofluorescence/Immunohistochemistry/Immunocytochemistry |
使用方法 | Published Applications: IP ICC/IF IHC WB See references for more information. Individual optimization may be required. |
供应商 | Active Motif |
纯化方式 | Protein G Chromatography |
免疫原 | This HIPK2 antibody was raised against a recombinant protein including amino acids 898-1051 of mouse HIPK2. |
背景 | HIPK2 (Homeodomain Interacting Protein Kinase 2) is a serine/threonine kinase present in the nucleus that interacts with homeodomain transcription factors and acts as a co-repressor of transcription. It inhibits cell growth, as well as promotes apoptosis through the phosphorylation and subsequent degradation of the anti-apoptotic factor CTBP1. HIPK2 also phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity. |
运输条件 | Blue Ice |
存放说明 | Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
存储溶液 | Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
计算分子量 | 130 kDa |
参考文献 |
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