Monoamine Oxidase B (MAO-B) Inhibitor Screening Kit (Fluorometric)
货号：
K797-100 基本售价：
6310.5 元 规格：
100assays
产品信息
概述| 货号 | K797-100 |
| 描述 | Monoamine oxidases (MAO, EC 1.4.3.4) are a family of enzymes that can oxidize a wide variety of endogenous primary amines. Two isoforms, MAO-A and MAO-B, have been identified based on their substrate, inhibitor specificity, and tissue localization. MAO-B can oxidize primary amines, but its list of specific substrates (i.e. benzylamine, phenylethylamine) is more limited compared to MAO-A. MAO-B is a mitochondrial-bound enzyme that is ubiquitously expressed throughout the brain and other tissues. It has been investigated in numerous studies including Parkinson’s disease, Alzheimer’s, and tobacco addiction. Specific MAO-B inhibitors such as selegiline, & rasagiline have been used to treat Parkinson’s patients, but their benefits are considered rather modest. BioVision’s MAO-B Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of MAO-B inhibitors. The assay is based on the fluorometric detection of H2O2, one of the byproducts generated during the oxidative deamination of MAO substrate. |
| 同种亚型 | Rabbit IgG |
| 来源宿主 | Rabbit |
性能| 供应商 | Biovision |
| 检测类型 | Fluorescence (Ex/Em = 535/587 nm)• Applications - Screening/studying/characterizing MAO-B inhibitors |
| 产品特色 | • Rapid & sensitive • High-throughput assay to screen/study/characterize potential inhibitors of monoamine oxidase B• Includes Inhibitor Control [Selegiline] |
| 试剂盒组分 | • MAO-B Assay Buffer• OxiRedTM Probe (in DMSO)• MAO-B Enzyme• MAO-B Substrate • Developer • Inhibitor Control (Selegiline) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
