Human Proinsulin Quantikine ELISA Kit (1 KT)
货号：
DPINS0 基本售价：
7217.7 元 规格：
1 Kit
产品信息
概述| 货号 | DPINS0 |
| 描述 | The Quantikine Human Proinsulin Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Proinsulin in serum and plasma. It contains E.coli-expressed recombinant human Proinsulin and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Proinsulin showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Proinsulin. |
| 别名 | IDDM2; ILPR; insulin; IRDN; MODY10; proinsulin; |
| 反应种属 | Human |
| 目标/特异性 | Natural and recombinant human Proinsulin. |
性能| 供应商 | R&D Systems |
| 检测类型 | Solid Phase Sandwich ELISA |
| Entrez Gene IDs | 3630 (Human); 16333 (Mouse) |
| 生物活性 | < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested. |
| 背景 | Insulin is a peptide hormone that is critical for glucose homeostasis. The mature Insulin peptide is derived from Proinsulin, which includes the Insulin A and B chains connected by a peptide fragment (Insulin C-peptide). Proinsulin is processed within the endoplasmic reticulum of pancreatic beta cells into equimolar ratios of mature Insulin and Insulin C-peptide. Proinsulin binds the Insulin Receptor A isoform (IR-A) with high affinity resulting in cell proliferation and migration. It has low binding affinity for the Insulin Receptor B isoform (IR-B) and the Insulin-like Growth Factor I Receptor (IGF R1). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Diabetes
- Glucose Homeostasis
- Growth Hormone/IGF-I Axis
- ICC / IHC Images: Proinsulin
- Nutrition and Appetite
- Pancreatic Endoderm
- Pancreatic Endoderm Cell Markers
- Protein/Peptide Hormones and Regulators
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