| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. High IFN-gamma and low SLPI mark severe asthma in mice and humans.
Authors: Raundhal M, Morse C, Khare A, Oriss T, Milosevic J, Trudeau J, Huff R, Pilewski J, Holguin F, Kolls J, Wenzel S, Ray P, Ray A
J Clin Invest, 2015;125(8):3037-50.
Species: Human
Sample Type: Cell Culture Supernates
Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study.
Authors: Smith-McCune K, Chen J, Greenblatt R, Shanmugasundaram U, Shacklett B, Hilton J, Johnson B, Irwin J, Giudice L
PLoS ONE, 2015;10(7):e0129769.
Species: Human
Sample Type: Endocervical Wick
Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
Authors: Suh HS, Choi N, Tarassishin L, Lee SC
PLoS ONE, 2012;7(4):e35115.
Species: Human
Sample Type: Cell Culture Supernates
The relationship between secretory leukocyte protease inhibitor expression and Epstein-Barr virus status among patients with nasopharyngeal carcinoma.
Authors: Tse KP, Wu CS, Hsueh C
Anticancer Res., 2012;32(4):1299-307.
Species: Human
Sample Type: Serum
Secretory leukocyte protease inhibitor (SLPI) expression and tumor invasion in oral squamous cell carcinoma.
Authors: Wen J, Nikitakis NG, Chaisuparat R, Greenwell-Wild T, Gliozzi M, Jin W, Adli A, Moutsopoulos N, Wu T, Warburton G, Wahl SM
Am. J. Pathol., 2011;178(6):2866-78.
Species: Human
Sample Type: Cell Culture Supernates
A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel.
Authors: Keller MJ, Madan RP, Torres NM
PLoS ONE, 2011;6(1):e16475.
Species: Human
Sample Type: cervicovaginal lavage
Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients.
Authors: Nicol GR, Han M, Kim J, Birse CE, Brand E, Nguyen A, Mesri M, FitzHugh W, Kaminker P, Moore PA, Ruben SM, He T
Mol. Cell Proteomics, 2008;7(10):1974-82.
Species: Human
Sample Type: Serum
The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils.
Authors: Jacobsen LC, Sorensen OE, Cowland JB, Borregaard N, Theilgaard-Monch K
J. Leukoc. Biol., 2008;83(5):1155-64.
Species: Human
Sample Type: Cell Lysates
Bacterial vaginosis, not HIV, is primarily responsible for increased vaginal concentrations of proinflammatory cytokines.
Authors: Mitchell CM, Balkus J, Agnew KJ, Cohn S, Luque A, Lawler R, Coombs RW, Hitti JE
AIDS Res. Hum. Retroviruses, 2008;24(5):667-71.
Species: Human
Sample Type: Vaginal Fluid
Overexpression of a secretory leukocyte protease inhibitor in human gastric cancer.
Authors: Cheng WL, Wang CS, Huang YH, Liang Y, Lin PY, Hsueh C, Wu YC, Chen WJ, Yu CJ, Lin SR, Lin KH
Int. J. Cancer, 2008;123(8):1787-96.
Species: Human
Sample Type: Plasma
An integrated clinical-genomics approach identifies a candidate multi-analyte blood test for serous ovarian carcinoma.
Authors: Meinhold-Heerlein I, Bauerschlag D, Zhou Y, Sapinoso LM, Ching K, Frierson H, Brautigam K, Sehouli J, Stickeler E, Konsgen D, Hilpert F, von Kaisenberg CS, Pfisterer J, Bauknecht T, Jonat W, Arnold N, Hampton GM
Clin. Cancer Res., 2007;13(2):458-66.
Species: Human
Sample Type: Serum
PRO 2000 elicits a decline in genital tract immune mediators without compromising intrinsic antimicrobial activity.
Authors: Keller MJ, Guzman E, Hazrati E, Kasowitz A, Cheshenko N, Wallenstein S, Cole AL, Cole AM, Profy AT, Wira CR, Hogarty K, Herold BC
AIDS, 2007;21(4):467-76.
Species: Human
Sample Type: cervicovaginal lavage
Mucosal innate immune factors in secretions from high-risk individuals immunized with a bivalent gp120 vaccine.
Authors: Cummins JE, Denniston M, Mayer KH, Pickard R, Novak RM, Graham P, Gurwith M, Orelind K, Ackers ML, Dezzutti CS
AIDS Res. Hum. Retroviruses, 2007;23(5):748-54.
Species: Human
Sample Type: Serum
Arginine-specific gingipains from Porphyromonas gingivalis deprive protective functions of secretory leucocyte protease inhibitor in periodontal tissue.
Authors: Into T, Inomata M, Kanno Y, Matsuyama T, Machigashira M, Izumi Y, Imamura T, Nakashima M, Noguchi T, Matsushita K
Clin. Exp. Immunol., 2006;145(3):545-54.
Species: Human
Sample Type: Cell Culture Supernates
Differential proteolytic enzyme activity in eosinophilic and neutrophilic asthma.
Authors: Simpson JL, Scott RJ, Boyle MJ, Gibson PG
Am. J. Respir. Crit. Care Med., 2005;172(5):559-65.
Species: Human
Sample Type: Sputum
Salivary secretory leukocyte protease inhibitor and oral candidiasis in human immunodeficiency virus type 1-infected persons.
Authors: Chattopadhyay A, Gray LR, Patton LL, Caplan DJ, Slade GD, Tien HC, Shugars DC
Infect. Immun., 2004;72(4):1956-63.
Species: Human
Sample Type: Saliva
Salivary secretory leukocyte protease inhibitor is associated with reduced transmission of human immunodeficiency virus type 1 through breast milk.
Authors: Farquhar C, VanCott TC, Mbori-Ngacha DA, Horani L, Bosire RK, Kreiss JK, Richardson BA, John-Stewart GC
J. Infect. Dis., 2002;186(8):1173-6.
Species: Human
Sample Type: Saliva
Effect of fluticasone on the elastase:antielastase profile of the normal lung.
Authors: Kamal AM, Corrigan CJ, Tetley TD, Alaghband-Zadeh J, Smith SF
Eur. J. Clin. Invest., 2002;32(9):713-9.
Species: Human
Sample Type: Upper Alveolar Lavage
Passive transfer of scrub typhus plasma to patients with AIDS: a descriptive clinical study.
Authors: Watt G, Kantipong P, Jongsakul K, de Souza M, Burnouf T
QJM, 2001;94(11):599-607.
Species: Human
Sample Type: Plasma
Relationship between airway inflammation and the frequency of exacerbations in patients with smoking related COPD.
Authors: Gompertz S, Bayley DL, Hill SL, Stockley RA
Thorax, 2001;56(1):36-41.
Species: Human
Sample Type: Saliva
Secretory leukocyte protease inhibitor inhibits infection of monocytes and lymphocytes with human immunodeficiency virus type 1 but does not interfere with transcytosis of cell-associated virus across tight epithelial barriers.
Authors: Hocini H, Becquart P, Bouhlal H, Adle-Biassette H, Kazatchkine MD, Belec L
Clin. Diagn. Lab. Immunol., 2000;7(3):515-8.
Species: Human
Sample Type: cervicovaginal lavage
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