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Porcine CXCL8/IL-8 Quantikine ELISA Kit (1 KT)

货号: P8000 基本售价: 6791.4 元 规格: 1 Kit

产品信息

概述
货号P8000
描述The Quantikine Porcine IL-8 Immunoassay is a 4.5 hour solid phase ELISA designed to measure porcine IL-8 in cell culture supernates and serum. It utilizes E. coli-expressed recombinant porcine IL-8 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately measure or quantify the recombinant porcine IL-8. Results obtained using natural porcine IL-8 show dose response curves that are parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural porcine IL-8.
别名3-10C; AMCF-I; C-X-C motif chemokine 8; CXCL8SCYB8; Emoctakin; GCP1; GCP-1TSG-1; IL8; interleukin 8; K60; LAI; LECT; MDNCF; MDNCFb-ENAP; member 8; MONAPGCP1; NAP1; NAP-1NAP1; NCF; Neutrophil-activating protein 1; Protein 3-10C; T cell chemotactic factor; T-cell chemotactic factor; TCF; TSG1;
全称
Interleukin 8
反应种属Porcine
目标/特异性Natural and recombinant porcine IL-8
性能
供应商R&D Systems
检测类型Solid Phase Sandwich ELISA
Entrez Gene IDs
3576 (Human); 396880 (Porcine); 403850 (Canine); 493836 (Feline)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1.
Authors: Schaefers MM, Breshears LM, Anderson MJ, Lin YC, Grill AE, Panyam J, Southern PJ, Schlievert PM, Peterson ML
PLoS ONE, 2012;7(3):e32813.
Species: Porcine
Sample Type: Cell Culture Supernates

Efficacy of linezolid compared to vancomycin in an experimental model of pneumonia induced by methicillin-resistant Staphylococcus aureus in ventilated pigs.
Authors: Martinez-Olondris P, Rigol M, Soy D, Guerrero L, Agusti C, Quera MA, Li Bassi G, Esperatti M, Luque N, Liapikou M, Filella X, Marco F, de la Bellacasa JP, Torres A
Crit. Care Med., 2012;40(1):162-8.
Species: Porcine
Sample Type: Serum

Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota.
Authors: Riboulet-Bisson E, Sturme MH, Jeffery IB
PLoS ONE, 2012;7(2):e31113.
Species: Porcine
Sample Type: Serum

Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans.
Authors: Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD, Nunn MA, Mollnes TE
J. Immunol., 2011;187(9):4913-9.
Species: Porcine
Sample Type: Plasma

Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis.
Authors: Hellerud BC, Nielsen EW, Thorgersen EB, Lindstad JK, Pharo A, Tonnessen TI, Castellheim A, Mollnes TE, Brandtzaeg P
Crit. Care Med., 2010;38(6):1467-74.
Species: Porcine
Sample Type: Plasma

Plasma concentrations of inflammatory cytokines rise rapidly during ECMO-related SIRS due to the release of preformed stores in the intestine.
Authors: McILwain RB, Timpa JG, Kurundkar AR
Lab. Invest., 2010;90(1):128-39.
Species: Porcine
Sample Type: Plasma

CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs.
Authors: Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tonnessen TI, Johansen HT, Castellheim A, Mollnes TE
FASEB J., 2010;24(3):712-22.
Species: Porcine
Sample Type: Plasma

Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues.
Authors: Wall R, Ross RP, Shanahan F, OMahony L, OMahony C, Coakley M, Hart O, Lawlor P, Quigley EM, Kiely B, Fitzgerald GF, Stanton C
Am. J. Clin. Nutr., 2009;89(5):1393-401.
Species: Porcine
Sample Type: Cell Culture Supernates

Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model.
Authors: Saethre M, Schneider MK, Lambris JD, Magotti P, Haraldsen G, Seebach JD, Mollnes TE
J. Immunol., 2008;180(9):6346-53.
Species: Porcine
Sample Type: Cell Culture Supernates

Effects of glucocorticoids in ventilated piglets with severe pneumonia.
Authors: Sibila O, Luna CM, Agusti C, Baquero S, Gando S, Patron JR, Morato JG, Absi R, Bassi N, Torres A
Eur. Respir. J., 2008;32(4):1037-46.
Species: Porcine
Sample Type: Serum

Improved pulmonary function by acid sphingomyelinase inhibition in a newborn piglet lavage model.
Authors: von Bismarck P, Wistadt CF, Klemm K, Winoto-Morbach S, Uhlig U, Schutze S, Adam D, Lachmann B, Uhlig S, Krause MF
Am. J. Respir. Crit. Care Med., 2008;177(11):1233-41.
Species: Porcine
Sample Type: BALF

Experimental Pseudomonas aeruginosa pneumonia: evaluation of the associated inflammatory response.
Authors: Sibila O, Agusti C, Torres A, Baquero S, Gando S, Patron JR, Morato JG, Goffredo DH, Bassi N, Luna CM
Eur. Respir. J., 2007;30(6):1167-72.
Species: Porcine
Sample Type: Serum

Dietary fatty acid composition rather than vitamin E supplementation influence ex vivo cytokine and eicosanoid response of porcine alveolar macrophages.
Authors: Moller S, Lauridsen C
Cytokine, 2006;35(1):6-12.
Species: Porcine
Sample Type: Cell Culture Supernates

Fibrinogen induces chemotactic activity in endothelial cells.
Authors: Seeger FH, Blessing E, Gu L, Bornhold R, Denger S, Kreuzer J
Acta Physiol. Scand., 2002;176(2):109-15.
Species: Porcine
Sample Type: Cell Culture Supernates

Ex vivo adenoviral vector gene delivery results in decreased vector-associated inflammation pre- and post-lung transplantation in the pig.
Authors: Yeung JC, Wagnetz D, Cypel M, Rubacha M, Koike T, Chun YM, Hu J, Waddell TK, Hwang DM, Liu M, Keshavjee S
Mol. Ther., 212;20(6):1204-11.
Species: Porcine
Sample Type: Plasma

生物活性< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
背景CXCL8/Interleukin-8 is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. CXCL8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. CXCL8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. CXCL8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents CXCL8 interaction with CXCR1.
运输条件Blue Ice
存放说明4℃
参考文献
  • Adipocytokines
  • Cancer Biomarkers
  • Chemokines and Receptors
  • Chemokines and Receptors in Allergy and Asthma
  • Chemokines and Receptors in Angiogenesis
  • CXC Chemokines and Receptors
  • Diabetes
  • HIF Transcription Factors
  • ICC / IHC Images: CXCL8/IL-8
  • Infectious Diseases
  • Inflammatory Mediators
  • Macrophage Activation Markers
  • Megakaryocytes
  • Neuroinflammation
  • Platelets