R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Association between Placental Lesions, Cytokines and Angiogenic Factors in Pregnant Women with Preeclampsia Authors: Ingrid C Weel PLoS ONE, 2016;11(6):e0157584. Species: Human Sample Type: Tissue Homogenates
Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch PLoS ONE, 2016;11(4):e0153387. Species: Human Sample Type: Cell Culture Supernates
Unexpected Normal Colloid Osmotic Pressure in Clinical States with Low Serum Albumin PLoS ONE, 2016;11(7):e0159839. Species: Human Sample Type: Serum
Cell surface-anchored syndecan-1 ameliorates intestinal inflammation and neutrophil transmigration in ulcerative colitis J Cell Mol Med, 2016;0(0):. Species: Human Sample Type: Serum
Innovative Flow Cytometry Allows Accurate Identification of Rare Circulating Cells Involved in Endothelial Dysfunction PLoS ONE, 2016;11(8):e0160153. Species: Human Sample Type: Plasma
Simple Plex() : A Novel Multi-Analyte, Automated Microfluidic Immunoassay Platform for the Detection of Human and Mouse Cytokines and Chemokines. Authors: Aldo P, Marusov G, Svancara D, David J, Mor G Am J Reprod Immunol, 2016;75(6):678-93. Species: Human Sample Type: Plasma
Cross-talk between intestinal epithelial cells and immune cells in inflammatory bowel disease Sci Rep, 2016;6(0):29783. Species: Human Sample Type: Cell Culture Supernates
Subclinical Inflammation and Endothelial Dysfunction in Young Patients with Diabetes: A Study from United Arab Emirates PLoS ONE, 2016;11(7):e0159808. Species: Human Sample Type: Serum
Nuclear DNA damage-triggered NLRP3 inflammasome activation promotes UVB-induced inflammatory responses in human keratinocytes Authors: Tatsuya Hasegawa Biochem Biophys Res Commun, 2016;0(0):. Species: Human Sample Type: Cell Culture Supernates
Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells. Authors: Strobel B, Klauser B, Hartig J, Lamla T, Gantner F, Kreuz S Mol Ther, 2015;23(10):1582-91. Species: Human Sample Type: Cell Culture Supernates
Sexual dimorphism in miR-210 expression and mitochondrial dysfunction in the placenta with maternal obesity. Authors: Muralimanoharan S, Guo C, Myatt L, Maloyan A Int J Obes (Lond), 2015;39(8):1274-81. Species: Human Sample Type: Tissue Homogenates
The Association between Serum Cytokines and Damage to Large and Small Nerve Fibers in Diabetic Peripheral Neuropathy. Authors: Magrinelli F, Briani C, Romano M, Ruggero S, Toffanin E, Triolo G, Peter G, Praitano M, Lauriola M, Zanette G, Tamburin S J Diabetes Res, 2015;2015(0):547834. Species: Human Sample Type: Serum
Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1beta Release. Authors: Hecker A, Kullmar M, Wilker S, Richter K, Zakrzewicz A, Atanasova S, Mathes V, Timm T, Lerner S, Klein J, Kaufmann A, Bauer S, Padberg W, Kummer W, Janciauskiene S, Fronius M, Schweda E, Lochnit G, Grau V J Immunol, 2015;195(5):2325-34. Species: Human Sample Type: Cell Culture Supernates
WNT5A transforms intestinal CD8alphaalpha(+) IELs into an unconventional phenotype with pro-inflammatory features. Authors: Zhao D, Xu A, Dai Z, Peng J, Zhu M, Shen J, Zheng Q, Ran Z BMC Gastroenterol, 2015;15(0):173. Species: Mouse Sample Type: Cell Culture Supernates
Blockade of PD-1 or p38 MAP kinase signaling enhances senescent human CD8(+) T-cell proliferation by distinct pathways. Authors: Henson S, Macaulay R, Riddell N, Nunn C, Akbar A Eur J Immunol, 2015;45(5):1441-51. Species: Human Sample Type: Cell Culture Supernates
The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production. Authors: Pundir P, MacDonald C, Kulka M J Immunol, 2015;195(6):2774-87. Species: Human Sample Type: Cell Culture Supernates
Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages. Authors: Sokolowska M, Chen L, Liu Y, Martinez-Anton A, Qi H, Logun C, Alsaaty S, Park Y, Kastner D, Chae J, Shelhamer J J Immunol, 2015;194(11):5472-87. Species: Human Sample Type: Cell Culture Supernates
Serum levels of inflammatory markers in depressed elderly patients with diabetes and mild cognitive impairment. Authors: Gorska-Ciebiada M, Saryusz-Wolska M, Borkowska A, Ciebiada M, Loba J PLoS ONE, 2015;10(3):e0120433. Species: Human Sample Type: Serum
The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses. Authors: Osei-Owusu P, Jessen Condry D, Toosky M, Roughead W, Bradley D, Nilles M Infect Immun, 2015;83(4):1507-22. Species: Human Sample Type: Cell Culture Supernates
Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance. Authors: Sasaki Y, Ohta M, Desai D, Figueiredo J, Whelan M, Sugano T, Yamabi M, Yano W, Faits T, Yabusaki K, Zhang H, Mlynarchik A, Inoue K, Mizuno K, Aikawa M PLoS ONE, 2015;10(7):e0131176. Species: Human Sample Type: Cell Culture Supernates
The inflammation, vascular repair and injury responses to exercise in fit males with and without Type 1 diabetes: an observational study. Authors: West D, Campbell M, Gonzalez J, Walker M, Stevenson E, Ahmed F, Wijaya S, Shaw J, Weaver J Cardiovasc Diabetol, 2015;14(0):71. Species: Human Sample Type: Plasma
Dysregulated choline metabolism in T-cell lymphoma: role of choline kinase-alpha and therapeutic targeting. Authors: Xiong J, Bian J, Wang L, Zhou J, Wang Y, Zhao Y, Wu L, Hu J, Li B, Chen S, Yan C, Zhao W Blood Cancer J, 2015;5(0):287. Species: Human Sample Type: Cell Culture Supernates
Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis. Authors: Wendling D, Abbas W, Godfrin-Valnet M, Kumar A, Guillot X, Khan K, Vidon C, Coquard L, Toussirot E, Prati C, Herbein G PLoS ONE, 2015;10(3):e0119981. Species: Human Sample Type: Serum
Vitamin D insufficiency and subclinical atherosclerosis in non-diabetic males living with HIV. Authors: Portilla J, Moreno-Perez O, Serna-Candel C, Escoin C, Alfayate R, Reus S, Merino E, Boix V, Giner L, Sanchez-Paya J, Pico A J Int AIDS Soc, 2014;17(0):18945. Species: Human Sample Type: Serum
Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner. Authors: Xu H, Lai W, Zhang Y, Liu L, Luo X, Zeng Y, Wu H, Lan Q, Chu Z BMC Cancer, 2014;14(0):330. Species: Human Sample Type: Cell Culture Supernates
Mucosal biomarkers of colorectal cancer risk do not increase at 6 months following sleeve gastrectomy, unlike gastric bypass. Authors: Kant P, Perry S, Dexter S, Race A, Loadman P, Hull M Obesity (Silver Spring), 2014;22(1):202-10. Species: Human Sample Type: Serum
Systemic upregulation of PDGF-B in patients with neovascular AMD. Authors: Zehetner C, Kirchmair R, Neururer S, Kralinger M, Bechrakis N, Kieselbach G Invest Ophthalmol Vis Sci, 2014;55(1):337-44. Species: Human Sample Type: Plasma
Bacteria induce prolonged PMN survival via a phosphatidylcholine-specific phospholipase C- and protein kinase C-dependent mechanism. Authors: Erttmann S, Gekara N, Fallman M PLoS ONE, 2014;9(1):e87859. Species: Human Sample Type: Cell Culture Supernates
HIV-1 Nef impairs key functional activities in human macrophages through CD36 downregulation. Authors: Olivetta E, Tirelli V, Chiozzini C, Scazzocchio B, Romano I, Arenaccio C, Sanchez M PLoS ONE, 2014;9(4):e93699. Species: Human Sample Type: Cell Culture Supernates
The impact of concomitant pulmonary infection on immune dysregulation in Pneumocystis jirovecii pneumonia. Authors: Chou C, Lin F, Tsai H, Chang S BMC Pulm Med, 2014;14(0):182. Species: Human Sample Type: BALF
High activities of BACE1 in brains with mild cognitive impairment. Authors: Cheng X, He P, Lee T, Yao H, Li R, Shen Y Am J Pathol, 2014;184(1):141-7. Species: Human Sample Type: Tissue Homogenates
Positive feedback between NF-kappaB and TNF-alpha promotes leukemia-initiating cell capacity. Authors: Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M J Clin Invest, 2014;124(2):528-42. Species: Human Sample Type: Whole Cells
Metabolic implications when employing heavy pre- and post-exercise rapid-acting insulin reductions to prevent hypoglycaemia in type 1 diabetes patients: a randomised clinical trial. Authors: Campbell M, Walker M, Trenell M, Luzio S, Dunseath G, Tuner D, Bracken R, Bain S, Russell M, Stevenson E, West D PLoS ONE, 2014;9(5):e97143. Species: Human Sample Type: Serum
Identification of a distinct glucocorticosteroid-insensitive pulmonary macrophage phenotype in patients with chronic obstructive pulmonary disease. Authors: Chana K, Fenwick P, Nicholson A, Barnes P, Donnelly L J Allergy Clin Immunol, 2014;133(1):207-16.e1-11. Species: Human Sample Type: cell culture supernate
Icariin ameliorates cigarette smoke induced inflammatory responses via suppression of NF-kappaB and modulation of GR in vivo and in vitro. Authors: Li L, Sun J, Xu C, Zhang H, Wu J, Liu B, Dong J PLoS ONE, 2014;9(8):e102345. Species: Human Sample Type: Cell Culture Supernates
Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. Authors: Todd J, Simpson P, Estis J, Torres V, Wub A Cytokine, 2013;64(3):660-5. Species: Human Sample Type: Plasma
Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor. Authors: Suzuki M, Takaishi S, Nagasaki M, Onozawa Y, Iino I, Maeda H, Komai T, Oda T J Biol Chem, 2013;288(15):10684-91. Species: Human Sample Type: Cell Culture Supernates
Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages. Authors: Haselow K, Bode J, Wammers M, Ehlting C, Keitel V, Kleinebrecht L, Schupp A, Haussinger D, Graf D J Leukoc Biol, 2013;94(6):1253-64. Species: Human Sample Type: cell culture supernate
Protein carbamylation predicts mortality in ESRD. Authors: Koeth R, Kalantar-Zadeh K, Wang Z, Fu X, Tang W, Hazen S , 2013;0(0):. Species: Human Sample Type: Serum
Preeclamptic plasma induces transcription modifications involving the AP-1 transcriptional regulator JDP2 in endothelial cells. Authors: Calicchio R, Buffat C, Mathieu J, Ben Salem N, Mehats C, Jacques S, Hertig A, Berkane N, Grevoul-Fresquet J, Simeoni U, Peyssonnaux C, Gavard J, Vaiman D, Miralles F Am J Pathol, 2013;183(6):1993-2006. Species: Human Sample Type: Plasma
Cleaved/associated TLR3 represents the primary form of the signaling receptor. Authors: Toscano F, Estornes Y, Virard F, Garcia-Cattaneo A, Pierrot A, Vanbervliet B, Bonnin M, Ciancanelli M, Zhang S, Funami K, Seya T, Matsumoto M, Pin J, Casanova J, Renno T, Lebecque S J Immunol, 2013;190(2):764-73. Species: Human Sample Type: cell culture supernate
CLEC5A is critical for dengue virus-induced inflammasome activation in human macrophages. Authors: Wu M, Chen S, Yang A, Lin W, Lin Y, Chen N, Tsai I, Li L, Hsieh S Blood, 2013;121(1):95-106. Species: Human Sample Type: Cell Culture Supernates
Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation. Authors: Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K Infect Immun, 2012;80(11):3795-803. Species: Human Sample Type: Cell Lysates
Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation. J Transl Med, 2012;10(0):95. Species: Human Sample Type: Cell Culture Supernates
Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function. Authors: Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK J. Immunol., 2012;188(3):1002-10. Species: Human Sample Type: Cell Culture Supernates
Suppression of NF-kappaB Reduces Myocardial No-Reflow. Authors: Zeng M, Yan H, Chen Y, Zhao H, Lv Y, Liu C, Zhou P, Zhao B PLoS ONE, 2012;7(10):e47306. Species: Human Sample Type: Cell Culture Supernates
A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment. Authors: Kulbe H, Chakravarty P, Leinster DA, Charles KA, Kwong J, Thompson RG, Coward JI, Schioppa T, Robinson SC, Gallagher WM, Galletta L, Salako MA, Smyth JF, Hagemann T, Brennan DJ, Bowtell DD, Balkwill FR Cancer Res., 2012;72(1):66-75. Species: Human Sample Type: Cell Culture Supernates
Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses. Authors: Andersson M, Lutay N, Hallgren O, Westergren-Thorsson G, Svensson M, Godaly G Innate Immun, 2012;18(3):531-40. Species: Human Sample Type: Cell Culture Supernates
Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. Authors: Djafarzadeh R, Sauter M, Notohamiprodjo S, Noessner E, Goyal P, Siess W, Wornle M, Ribeiro A, Himmelein S, Sitter T, Nelson PJ PLoS ONE, 2012;7(4):e33963. Species: Human Sample Type: Cell Culture Supernates
Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor. Authors: Churchman SM, Geiler J, Parmar R, Horner EA, Church LD, Emery P, Buch MH, McDermott MF, Ponchel F Clin. Exp. Rheumatol., 2012;30(4):534-42. Species: Human Sample Type: Serum
A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-kappaB signaling and improves survival in mouse models of sepsis. Acta Pharmacol. Sin., 2012;33(9):1204-16. Species: Human Sample Type: Cell Culture Supernates
High levels of beta-catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway. Authors: Liu N, Shi S, Deng M, Tang L, Zhang G, Liu N, Ding B, Liu W, Liu Y, Shi H, Liu L, Jin Y J. Bone Miner. Res., 2011;26(9):2082-95. Species: Human Sample Type: Cell Culture Supernates
HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells. Authors: Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC Leukemia, 2011;25(1):161-8. Species: Human Sample Type: Cell Culture Supernates
Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients. Authors: Nakajima H, Nakajima K, Tarutani M, Morishige R, Sano S Arch. Dermatol. Res., 2011;303(6):451-5. Species: Human Sample Type: Serum
TWEAK Induces Apoptosis through a Death-signaling Complex Comprising Receptor-interacting Protein 1 (RIP1), Fas-associated Death Domain (FADD), and Caspase-8. Authors: Ikner A, Ashkenazi A J. Biol. Chem., 2011;286(24):21546-54. Species: Human Sample Type: Cell Culture Supernates
Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production. Authors: Khoo AL, Chai LY, Koenen HJ, Oosting M, Steinmeyer A, Zuegel U, Joosten I, Netea MG, van der Ven AJ Cytokine, 2011;55(2):294-300. Species: Human Sample Type: Cell Culture Supernates
Decoy receptor 3 levels in peripheral blood predict outcomes of acute respiratory distress syndrome. Authors: Chen CY, Yang KY, Chen MY, Chen HY, Lin MT, Lee YC, Perng RP, Hsieh SL, Yang PC, Chou TY Am. J. Respir. Crit. Care Med., 2009;180(8):751-60. Species: Human Sample Type: Plasma
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. Authors: Duncan JA, Gao X, Huang MT, OConnor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, Ting JP J. Immunol., 2009;182(10):6460-9. Species: Human Sample Type: Cell Culture Supernates
Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. Authors: Mabilleau G, Sabokbar A PLoS ONE, 2009;4(1):e4173. Species: Human Sample Type: Cell Culture Supernates
In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes. Authors: Lachmann HJ, Lowe P, Felix SD, Rordorf C, Leslie K, Madhoo S, Wittkowski H, Bek S, Hartmann N, Bosset S, Hawkins PN, Jung T J. Exp. Med., 2009;206(5):1029-36. Species: Human Sample Type: Plasma
Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism. Authors: Semiramoth N, Gleizes A, Turbica I, Sandre C, Gorges R, Kansau I, Servin A, Chollet-Martin S J. Leukoc. Biol., 2009;85(2):310-21. Species: Human Sample Type: Cell Culture Supernates
Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells. Authors: Oh JY, Kim MK, Shin MS, Wee WR, Lee JH Cytokine, 2009;46(1):100-3. Species: Human Sample Type: Cell Culture Supernates
Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis. Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P Circ. Res., 2009;104(1):60-8. Species: Human Sample Type: Cell Culture Supernates
Immuno-inflammatory and thrombotic/fibrinolytic variables associated with acute ischemic stroke diagnosis. Authors: Tuttolomondo A, Pinto A, Corrao S, Di Raimondo D, Fernandez P, Di Sciacca R, Arnao V, Licata G Atherosclerosis, 2009;203(2):503-8. Species: Human Sample Type: Plasma
Immuno-inflammatory predictors of stroke at follow-up in patients with chronic non-valvular atrial fibrillation (NVAF). Authors: Pinto A, Tuttolomondo A, Casuccio A, Di Raimondo D, Di Sciacca R, Arnao V, Licata G Clin. Sci., 2009;116(10):781-9. Species: Human Sample Type: Plasma
Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced disease. Authors: Lee WI, Liang FC, Huang JL, Jaing TH, Wang CH, Lin TY, Huang YC, Huang WL, Jou R, Hsieh MY, Chia JH, Wu TL J. Clin. Immunol., 2009;29(3):319-29. Species: Human Sample Type: Cell Culture Supernates
KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis. Authors: Navenot JM, Fujii N, Peiper SC Mol. Pharmacol., 2009;75(5):1074-83. Species: Human Sample Type: Cell Culture Supernates
IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. Authors: Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A J. Allergy Clin. Immunol., 2009;123(1):59-66.e4. Species: Human Sample Type: Cell Culture Supernates
The novel lipopolysaccharide-binding protein CRISPLD2 is a critical serum protein to regulate endotoxin function. Authors: Wang ZQ, Xing WM, Fan HH, Wang KS, Zhang HK, Wang QW, Qi J, Yang HM, Yang J, Ren YN, Cui SJ, Zhang X, Liu F, Lin DH, Wang WH, Hoffmann MK, Han ZG J. Immunol., 2009;183(10):6646-56. Species: Human Sample Type: Cell Culture Supernates
Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4. Authors: Chase JC, Celli J, Bosio CM Infect. Immun., 2009;77(1):180-95. Species: Human Sample Type: Cell Culture Supernates
Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Authors: Samah B, Porcheray F, Gras G Clin. Exp. Immunol., 2008;151(3):476-86. Species: Human Sample Type: Cell Culture Supernates
Synergistic interactions between interferon-gamma and TRAIL modulate c-FLIP in endothelial cells, mediating their lineage-specific sensitivity to thrombotic thrombocytopenic purpura plasma-associated apoptosis. Authors: Stefanescu R, Bassett D, Modarresi R, Santiago F, Fakruddin M, Laurence J Blood, 2008;112(2):340-9. Species: Human Sample Type: Plasma
Mycobacterium bovis Bacillus Calmette-Guerin suppresses inflammatory Th2 responses by inducing functional alteration of TSLP-activated dendritic cells. Authors: Yokoi T, Amakawa R, Tanijiri T, Sugimoto H, Torii Y, Amuro H, Son Y, Tajima K, Liu YJ, Ito T, Fukuhara S Int. Immunol., 2008;20(10):1321-9. Species: Human Sample Type: Cell Culture Supernates
NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population. Authors: Zhang Y, Lin M, Zhang S, Wang Z, Jiang L, Shen J, Bai J, Gao F, Zhou M, Chen Q Cytokine, 2008;41(2):144-9. Species: Human Sample Type: Serum
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. Authors: Hartl D, Krauss-Etschmann S, Koller B, Hordijk PL, Kuijpers TW, Hoffmann F, Hector A, Eber E, Marcos V, Bittmann I, Eickelberg O, Griese M, Roos D J. Immunol., 2008;181(11):8053-67. Species: Human Sample Type: BALF
Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Authors: Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S Eur. J. Immunol., 2008;38(4):1012-23. Species: Human Sample Type: Cell Culture Supernates
Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Authors: Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ Proc. Natl. Acad. Sci. U.S.A., 2008;105(8):2865-70. Species: Human Sample Type: Bone Marrow Plasma
Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells. Authors: Scamuffa N, Siegfried G, Bontemps Y, Ma L, Basak A, Cherel G, Calvo F, Seidah NG, Khatib AM J. Clin. Invest., 2008;118(1):352-63. Species: Human Sample Type: Cell Culture Supernates
MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells. Authors: Le Quement C, Guenon I, Gillon JY, Lagente V, Boichot E Am. J. Physiol. Lung Cell Mol. Physiol., 2008;294(6):L1076-84. Species: Human Sample Type: Cell Culture Supernates
Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease. Authors: Chiang LY, Sheppard DC, Gravelat FN, Patterson TF, Filler SG Infect. Immun., 2008;76(8):3429-38. Species: Human Sample Type: Cell Culture Supernates
In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b. Authors: Paulsson JM, Dadfar E, Held C, Jacobson SH, Lundahl J Clin. Exp. Immunol., 2008;153(2):196-204. Species: Human Sample Type: blister fluid
High levels and inflammatory effects of soluble CXC ligand 16 (CXCL16) in coronary artery disease: down-regulatory effects of statins. Authors: Smith C, Halvorsen B, Otterdal K, Waehre T, Yndestad A, Fevang B, Sandberg WJ, Breland UM, Froland SS, Oie E, Gullestad L, Damas JK, Aukrust P Cardiovasc. Res., 2008;79(1):195-203. Species: Human Sample Type: Cell Culture Supernates
Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits. Authors: Aranha CC, Gupta SM, Reddy KV Cytokine, 2008;43(1):63-70. Species: Rabbit Sample Type: cervicovaginal lavage
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36. Authors: Nilsen NJ, Deininger S, Nonstad U, Skjeldal F, Husebye H, Rodionov D, von Aulock S, Hartung T, Lien E, Bakke O, Espevik T J. Leukoc. Biol., 2008;84(1):280-91. Species: Human Sample Type: Cell Culture Supernates
Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose. Authors: Harrison ML, Obermueller E, Maisey NR, Hoare S, Edmonds K, Li NF, Chao D, Hall K, Lee C, Timotheadou E, Charles K, Ahern R, King DM, Eisen T, Corringham R, DeWitte M, Balkwill F, Gore M J. Clin. Oncol., 2007;25(29):4542-9. Species: Human Sample Type: Plasma
Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. Authors: Lin YL, Liang YC, Chiang BL J. Leukoc. Biol., 2007;82(6):1473-80. Species: Human Sample Type: Cell Culture Supernates
Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1. Authors: Canault M, Leroyer AS, Peiretti F, Leseche G, Tedgui A, Bonardo B, Alessi MC, Boulanger CM, Nalbone G Am. J. Pathol., 2007;171(5):1713-23. Species: Human Sample Type: Cell Culture Supernates
Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-alpha in human osteoarthritic chondrocytes. Authors: Nah SS, Choi IY, Yoo B, Kim YG, Moon HB, Lee CK FEBS Lett., 2007;581(9):1928-32. Species: Human Sample Type: Cell Culture Supernates
Translocation of bacterial DNA from Gram-positive microorganisms is associated with a species-specific inflammatory response in serum and ascitic fluid of patients with cirrhosis. Authors: Frances R, Gonzalez-Navajas JM, Zapater P, Munoz C, Cano R, Pascual S, Santana F, Marquez D, Perez-Mateo M, Such J Clin. Exp. Immunol., 2007;150(2):230-7. Species: Human Sample Type: Serum
Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure. Authors: Kourea K, Parissis JT, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, Filippatos G, Kremastinos DT Atherosclerosis, 2007;199(1):215-21. Species: Human Sample Type: Plasma
Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake. Authors: Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, Bo S, Durazzo M, Cassader M Am. J. Clin. Nutr., 2007;86(3):661-71. Species: Human Sample Type: Serum
Newly recruited human monocytes have a preserved responsiveness towards bacterial peptides in terms of CD11b up-regulation and intracellular hydrogen peroxide production. Authors: Dadfar E, Jacobson SH, Lundahl J Clin. Exp. Immunol., 2007;148(3):573-82. Species: Human Sample Type: Serum
C-reactive protein induces endothelial cell apoptosis and matrix metalloproteinase-9 production in human mononuclear cells: Implications for the destabilization of atherosclerotic plaque. Authors: Nabata A, Kuroki M, Ueba H, Hashimoto S, Umemoto T, Wada H, Yasu T, Saito M, Momomura S, Kawakami M Atherosclerosis, 2007;196(1):129-35. Species: Human Sample Type: Cell Culture Supernates
Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells. Authors: Arnold R, Neumann M, Konig W Immunology, 2007;121(1):71-81. Species: Human Sample Type: Cell Culture Supernates
Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators. Authors: Orfanos SE, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C Crit. Care Med., 2007;35(1):199-206. Species: Human Sample Type: Serum
Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. Authors: Mian MF, Lauzon NM, Stampfli MR, Mossman KL, Ashkar AA J. Leukoc. Biol., 2007;83(3):774-84. Species: Human Sample Type: Cell Culture Supernates
The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection. Authors: Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N Fertil. Steril., 2007;90(1):60-4. Species: Human Sample Type: Follicular Fluid
TREM-1 expression in tumor-associated macrophages and clinical outcome in lung cancer. Authors: Ho CC, Liao WY, Wang CY, Lu YH, Huang HY, Chen HY, Chan WK, Chen HW, Yang PC Am. J. Respir. Crit. Care Med., 2007;177(7):763-70. Species: Human Sample Type: Whole Cells
In vitro and in vivo effects of salbutamol on neutrophil function in acute lung injury. Authors: Perkins GD, Nathani N, McAuley DF, Gao F, Thickett DR Thorax, 2007;62(1):36-42. Species: Human Sample Type: BALF
Panel of markers can accurately predict endometriosis in a subset of patients. Authors: Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT Fertil. Steril., 2007;89(5):1073-81. Species: Human Sample Type: Serum
Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease. Authors: Doucet M, Russell AP, Leger B, Debigare R, Joanisse DR, Caron MA, LeBlanc P, Maltais F Am. J. Respir. Crit. Care Med., 2007;176(3):261-9. Species: Human Sample Type: Plasma
Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis. Authors: Bae E, Kim WJ, Kang YM, Suk K, Koh EM, Cha HS, Ahn KS, Huh TL, Lee WH Clin. Exp. Immunol., 2007;148(3):410-8. Species: Human Sample Type: Cell Culture Supernates
Non-esterified fatty acid concentrations are independently associated with hepatic steatosis in obese subjects. Authors: Holt HB, Wild SH, Wood PJ, Zhang J, Darekar AA, Dewbury K, Poole RB, Holt RI, Phillips DI, Byrne CD Diabetologia, 2006;49(1):141-8. Species: Human Sample Type: Serum
Erythropoiesis abnormalities contribute to early-onset anemia in patients with septic shock. Authors: Claessens YE, Fontenay M, Pene F, Chiche JD, Guesnu M, Hababou C, Casadevall N, Dhainaut JF, Mira JP, Cariou A Am. J. Respir. Crit. Care Med., 2006;174(1):51-7. Species: Human Sample Type: Plasma
Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. Authors: Karrar A, Broome U, Uzunel M, Qureshi AR, Sumitran-Holgersson S Gut, 2006;56(2):243-52. Species: Human Sample Type: Cell Culture Supernates
The potential of adiponectin in driving arthritis. Authors: Ehling A, Schaffler A, Herfarth H, Tarner IH, Anders S, Distler O, Paul G, Distler J, Gay S, Scholmerich J, Neumann E, Muller-Ladner U J. Immunol., 2006;176(7):4468-78. Species: Human Sample Type: Cell Culture Supernates
Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease. Authors: Sheikine Y, Bang CS, Nilsson L, Samnegard A, Hamsten A, Jonasson L, Eriksson P, Sirsjo A Atherosclerosis, 2006;188(2):462-6. Species: Human Sample Type: Serum
Glycerol monolaurate inhibits the effects of Gram-positive select agents on eukaryotic cells. Authors: Peterson ML, Schlievert PM Biochemistry, 2006;45(7):2387-97. Species: Human Sample Type: Cell Culture Supernates
The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2. Authors: Gilleron M, Nigou J, Nicolle D, Quesniaux V, Puzo G Chem. Biol., 2006;13(1):39-47. Species: Human Sample Type: Cell Culture Supernates
No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease. Authors: Solheim S, Pettersen AA, Arnesen H, Seljeflot I Thromb. Haemost., 2006;96(5):660-4. Species: Human Sample Type: Serum
Proinflammatory cytokines, insulin resistance, and insulin secretion in chronic hepatitis C patients: A case-control study. Authors: Lecube A, Hernandez C, Genesca J, Simo R Diabetes Care, 2006;29(5):1096-101. Species: Human Sample Type: Serum
Th2 cytokine response in Major Depressive Disorder patients before treatment. Authors: Pavon L, Kiryushko D, Novitskaya V, Sandoval-Lopez G, Eugenia Hernandez M, Soroka V, Klingelhofer J, Loria F, Estrada I, Lukanidin E, Berezin V, Perez M, Moreno J, Bock E, Avila U, Leff P, Anton B, Heinze G J. Neuroimmunol., 2006;172(1):156-65. Species: Human Sample Type: Serum
Follistatin-like protein-1 is a novel proinflammatory molecule. Authors: Miyamae T, Marinov AD, Sowders D, Wilson DC, Devlin J, Boudreau R, Robbins P, Hirsch R J. Immunol., 2006;177(7):4758-62. Species: Human Sample Type: Cell Culture Supernates
Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells. Authors: Marquez-Martin A, De La Puerta R, Fernandez-Arche A, Ruiz-Gutierrez V, Yaqoob P Cytokine, 2006;36(5):211-7. Species: Human Sample Type: Cell Culture Supernates
Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Authors: Ebert EC, Mehta V Cell. Immunol., 2006;241(1):7-13. Species: Human Sample Type: Cell Culture Supernates
Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways. Authors: Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ Exp. Hematol., 2006;34(8):1115-24. Species: Human Sample Type: Cell Culture Supernates
Kinin receptor expression during Staphylococcus aureus infection. Authors: Bengtson SH, Phagoo SB, Norrby-Teglund A, Pahlman L, Morgelin M, Zuraw BL, Leeb-Lundberg LM, Herwald H Blood, 2006;108(6):2055-63. Species: Human Sample Type: Cell Culture Supernates
IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. Authors: Vaknin-Dembinsky A, Balashov K, Weiner HL J. Immunol., 2006;176(12):7768-74. Species: Human Sample Type: Cell Culture Supernates
Inhibitory effects of micronized fenofibrate on carotid atherosclerosis in patients with essential hypertension. Authors: Zhu S, Su G, Meng QH Clin. Chem., 2006;52(11):2036-42. Species: Human Sample Type: Serum
Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer. Authors: Ferrandina G, Ranelletti FO, Legge F, Salutari V, Martinelli E, Fattorossi A, Lorusso D, Zannoni G, Vellone V, Paglia A, Scambia G Clin. Cancer Res., 2006;12(7):2055-60. Species: Human Sample Type: Serum
Influence of eotaxin 67G>A polymorphism on plasma eotaxin concentrations in myocardial infarction survivors and healthy controls. Authors: Sheikine Y, Olsen B, Gharizadeh B, Jatta K, Tornvall P, Ghaderi M Atherosclerosis, 2006;189(2):458-63. Species: Human Sample Type: Serum
Growth hormone-induced reduction of soluble apoptosis mediators is associated with reverse cardiac remodelling and improvement of exercise capacity in patients with idiopathic dilated cardiomyopathy. Authors: Parissis JT, Adamopoulos S, Karatzas D, Paraskevaidis J, Livanis E, Kremastinos D Eur J Cardiovasc Prev Rehabil, 2005;12(2):164-8. Species: Human Sample Type: Plasma
Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism. Authors: Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH Clin. Chem., 2005;51(3):578-85. Species: Human Sample Type: Plasma
Immune responses induced by intranasal imiquimod and implications for therapeutics in rhinovirus infections. Authors: Clejan S, Mandrea E, Pandrea IV, Dufour J, Japa S, Veazey RS J. Cell. Mol. Med., 2005;9(2):457-61. Species: Primate - Macaca mulatta (Rhesus monkey) Sample Type: Nasal Fluid
Relationship between cytokines and the embryotoxicity of hydrosalpingeal fluid. Authors: Bedaiwy MA, Falcone T, Goldberg JM, Attaran M, Sharma R, Miller K, Nelson DR, Agarwal A J. Assist. Reprod. Genet., 2005;22(4):161-5. Species: Human Sample Type: Hypersalpingeal fluid (HSF)
Markers of immune activation and viral load in HIV-associated sensory neuropathy. Authors: Schifitto G, McDermott MP, McArthur JC, Marder K, Sacktor N, McClernon DR, Conant K, Cohen B, Epstein LG, Kieburtz K, Kieburtz K Neurology, 2005;64(5):842-8. Species: Human Sample Type: Plasma
Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Authors: Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA Blood, 2005;105(2):830-7. Species: Human Sample Type: Cell Lysates
Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage. Authors: Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, Mantz J, Desmonts JM, Gougerot-Pocidalo MA, Chollet-Martin S Crit. Care Med., 2005;33(6):1359-64. Species: Human Sample Type: Cell Culture Supernates
Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure. Authors: Roos-Engstrand E, Wallin A, Bucht A, Pourazar J, Sandstrom T, Blomberg A Eur. Respir. J., 2005;25(5):797-803.
Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men. Authors: Pagura SM, Thomas SG, Woodhouse LJ, Ezzat S, Marks P J. Orthop. Res., 2005;23(2):397-405. Species: Human Sample Type: Synovial Fluid
Aseptic peritonitis due to peptidoglycan contamination of pharmacopoeia standard dialysis solution. Authors: Martis L, Patel M, Giertych J, Mongoven J, Taminne M, Perrier MA, Mendoza O, Goud N, Costigan A, Denjoy N, Verger C, Owen WF Lancet, 2005;365(9459):588-94. Species: Human Sample Type: dialysate effluent
Influence of eicosapentaenoic acid, an omega-3 fatty acid, on ultraviolet-B generation of prostaglandin-E2 and proinflammatory cytokines interleukin-1 beta, tumor necrosis factor-alpha, interleukin-6 and interleukin-8 in human skin in vivo. Authors: Shahbakhti H, Watson RE, Azurdia RM, Ferreira CZ, Garmyn M, Rhodes LE Photochem. Photobiol., 2004;80(2):231-5. Species: Human Sample Type: Plasma
Effects of antiasthmatic agents on the functions of peripheral blood monocyte-derived dendritic cells from atopic patients. Authors: Saeki S, Matsuse H, Kondo Y, Machida I, Kawano T, Tomari S, Obase Y, Fukushima C, Kohno S J. Allergy Clin. Immunol., 2004;114(3):538-44. Species: Human Sample Type: Cell Culture Supernates
Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries. Authors: Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL J. Androl., 2004;25(2):250-4. Species: Human Sample Type: seminal plasma
Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus. Authors: Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N J. Virol., 2004;78(12):6151-61. Species: Primate - Pan troglodytes (Chimpanzee) Sample Type: Cell Culture Supernates
Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells. Authors: Kahlon KS, Brown C, Cooper LJ, Raubitschek A, Forman SJ, Jensen MC Cancer Res., 2004;64(24):9160-6. Species: Human Sample Type: Cell Culture Supernates
Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury. Authors: Hayakata T, Shiozaki T, Tasaki O, Ikegawa H, Inoue Y, Toshiyuki F, Hosotubo H, Kieko F, Yamashita T, Tanaka H, Shimazu T, Sugimoto H Shock, 2004;22(2):102-7. Species: Human Sample Type: Serum
Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis. Authors: McNamara PS, Flanagan BF, Selby AM, Hart CA, Smyth RL Eur. Respir. J., 2004;23(1):106-12. Species: Human Sample Type: BALF
Inflammation and nitric oxide production in skeletal muscle of type 2 diabetic patients. Authors: Torres SH, De Sanctis JB, de L Briceno M, Hernandez N, Finol HJ J. Endocrinol., 2004;181(3):419-27. Species: Human Sample Type: Tissue Homogenates
Antifungal immune reactivity in nasal polyposis. Authors: Pitzurra L, Bellocchio S, Nocentini A, Bonifazi P, Scardazza R, Gallucci L, Stracci F, Simoncelli C, Bistoni F, Romani L Infect. Immun., 2004;72(12):7275-81. Species: Human Sample Type: nasal lavage
Amniotic fluid tumor necrosis factor-alpha is a marker for the prediction of early-onset neonatal sepsis in preterm labor. Authors: Park KH, Yoon BH, Shim SS, Jun JK, Syn HC Gynecol. Obstet. Invest., 2004;58(2):84-90. Species: Human Sample Type: Amniotic Fluid
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Authors: Henkel JS, Engelhardt JI, Siklos L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH Ann. Neurol., 2004;55(2):221-35. Species: Human Sample Type: CSF
Role of transforming growth factor-beta in breast milk for initiation of IgA production in newborn infants. Authors: Ogawa J, Sasahara A, Yoshida T, Sira MM, Futatani T, Kanegane H, Miyawaki T Early Hum. Dev., 2004;77(1):67-75. Species: Human Sample Type: Colostrum
High concentrations of circulating macrophage migration inhibitory factor in patients with severe blunt trauma: Is serum macrophage migration inhibitory factor concentration a valuable prognostic factor? Authors: Chuang CC, Hung CJ, Tsai MC, Chuang YC Crit. Care Med., 2004;32(3):734-9. Species: Human Sample Type: Serum
Normal nasal mucociliary clearance in CF children: evidence against a CFTR-related defect. Authors: McShane D, Davies JC, Wodehouse T, Bush A, Geddes D, Alton EW Eur. Respir. J., 2004;24(1):95-100. Species: Human Sample Type: nasal lavage
Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. Authors: Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W J. Immunol., 2004;173(7):4433-42. Species: Human Sample Type: Cell Culture Supernates
Guiding the vaginal microbicide trials with biomarkers of inflammation. Authors: Fichorova RN J.
|