Steroid Receptor Coactivator-1 (SRC-1), (676-700), biotin labeled
货号:
AS-62152 基本售价:
3388.0 元 规格:
1mg
产品信息
性能供应商 | AnaSpec |
运输条件 | RT |
存放说明 | -20℃ |
纯度 | % Peak Area By HPLC ≥. 95% |
研究领域 | Signal Transduction Research |
参考文献 | This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminnaly biotinylated peptide is derived from the second LXXLL motif of SRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic beta-helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain. |
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