| 货号 | ES002 |
| 简介 | Substrate for MMP-3, MMP-10, Trypsin, HGF Activator, and Coagulation Factor X |
| 来源 | Mca-Arg-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(Dnp)-NH2 Mca: (7-Methoxycoumarin-4-yl)acetyl, Nval: Norvaline, Dnp:2, 4-Dinitrophenyl. |
| 产品组分 |
| 供应商 | R&D Systems |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage. | |
| 生物活性 | The peptide substrate contains a highly fluorescent7-methoxycoumarin group that is efficiently quenched by resonance energytransfer to the 2,4-dinitrophenyl group. It can be used to measure theactivities of peptidases that are capable of cleaving an amide bond between thefluorescent group and the quencher group, causing an increase in fluorescence. It is an excellent substrate for MMP-3 (stromelysin 1) andMMP-10 (stromelysin 2). The cleavage site is the peptide bond between Glu andNval (norvaline). It is also an excellent substrate for Trypsin, HGF activatorand factor Xa. |
| 运输条件 | Blue Ice |
| 预期分子量 | 1674 Da |
| 存放说明 | -20℃ |
| 纯度 | >95%, by HPLC. |
| 参考文献 |
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