Polyclonal CCL2/MCP1 Blocking Peptide - (Dry Ice)
货号：
NBP1-07034PEP 基本售价：
1219.4 元 规格：
0.05 mg
产品信息
概述| 货号 | NBP1-07034PEP |
| 反应种属 | HuSpecies Glossary |
| 目标/特异性 | This peptide is specific for NBP1-07034 only. |
性能| 供应商 | Novus |
| 免疫原 | Synthetic peptide made to an internal portion of rat MCP1 (within residues 30-80). [Swiss-Prot# P14844] |
| 背景 | MCP-1 (monocyte chemoattracctant protein-1, also called C-C motif chemokine 2 or CCL2) is a secreted protein belonging to intercrine beta (chemokine CC) family and it specifically act as a chemotactic factor to attracts monocytes, CD4+ T cells, NK cells as well as for CCR2 expressing cells, but not neutrophils. Both hematopoietic and non-hematopoietic cells that include monocytes/macrophages, dendritic cells, astrocytes, endothelial cells and fibroblasts express MCP-1, and monocytes/macrophages are the major source of MCP-1 in peripheral blood. Besides, expression at acute inflammation sites, MCP-1 is upregulated in chronic inflammation, including autoimmune disease, atherosclerosis, cancer, and chronic infection. MCP-1 has been implicated in both pro-inflammatory and anti-inflammatory responses, and is a potential intervention point for the treatment of various inflammatory/autoimmune diseases (multiple sclerosis, atherosclerosis, insulin-resistant diabetes, rheumatoid arthritis and lupus nephritis), cancers (breast and prostate cancer) and HIV-1/AIDS. |
| 运输条件 | Dry Ice |
| 存放说明 | Store at -80C. Avoid freeze-thaw cycles. |
| 存储溶液 | Peptide dissolved in dH2O. Contains no BSA. |
| 浓度 | 1.0 mg/ml |
