Rabbit RGS20 Antibody Pack
货号:
NBP2-25075 基本售价:
5462.9 元 规格:
-
产品信息
概述货号 | NBP2-25075 |
反应种属 | HuSpecies Glossary |
来源宿主 | Rabbit |
应用 | PEP-ELISA |
性能供应商 | Novus |
免疫原 | The following antibodies are included in this RGS20 antibody bundle: Antibody to RGS20; Format: Rabbit sera; Application: ELISA; Immunogen: amino acids 148-161Antibody to RGS20; Format: Rabbit sera; Application: ELISA; Immunogen: amino acids 1-15 Antibody to RGS20; Format: Rabbit sera; Application: ELISA; Immunogen: amino acids 30-48Antibody to RGS20; Format: Rabbit sera; Application: ELISA; Immunogen: amino acids 171-189 |
背景 | RGS proteins are regulatory and structural components GPCR complexes. These are GAPs for Gi and Gq class Galpha proteins and negatively regulate GPCR signaling pathways. RGS20, a 25KDa protein, is a member of this family and is human homolog of bovine Gz-GAP. It contains an N-terminal cysteine string that is potential site for multiple palmitoylation and a C-terminal RGS core domain. RGS20 plays a vital role in regulating GPCR signals in brain, neuronal development and regulation of golgi structure. RGS20 specifically interacts and accelerates the hydrolysis of G-alphaz. Reports suggest that RGS20 interacts with G-alphai subunit and plays a significant role in regulation of G-alphai-mediated signaling. It is a membrane-bound protein specifically expressed in brain, with highest concentrations in caudate nucleus and temporal lobe. |
存放说明 | Store at -20C. Avoid freeze-thaw cycles. |
纯度 | Unpurified |