| 货号 | MAB2495 |
| 别名 | EC 3.4.21; EC 3.4.21.-; EC 3.4.21.4; MGC141886; MGC148044; Spinesin; TMPRSS5; transmembrane protease serine 5; transmembrane protease, serine 5 |
| 反应种属 | Human |
| 应用 | Immunoprecipitation(25 µg/mL) |
| 目标/特异性 | Detects human Spinesin in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Spinesin is observed. |
| 使用方法 | Immunoprecipitation: 25 µg/mL Neutralization: Measured by its ability to neutralize Recombinant Human Spinesin (1 µg/mL, Catalog # 2495-SE) cleavage of the fluorogenic peptide substrate Boc-QAR-Amc (0.1 mM, Catalog # ES014). The Neutralization Dose (ND50) is typically 7 µg/mL. |
| 来源 | Monoclonal Mouse IgG2B Clone # 376608 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 80975 (Human); 80893 (Mouse) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Spinesin Tyr27-Leu413 Accession # Q0P514 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | Spinesin is a type II transmembrane serine protease (TTSP). TTSPs have emerged as an important group of cell surface proteases with key roles in converting protein precursors into mature and functional molecules. All TTSPs are synthesized as single-chain precursors and processed into disulfide bond-linked dimers. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|