| 货号 | MAB13501-SP |
| 简介 | Clone GoH3 was used by HLDA to establish CD designation |
| 别名 | CD49 antigen-like family member F; CD49f antigen; CD49f; DKFZp686J01244; FLJ18737; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6; ITGA6B; Platelet gpl; VLA-6 |
| 反应种属 | Human/Bovine/Mouse |
| 应用 | Flow Cytometry(2.5 µg/106cells) |
| 目标/特异性 | Detects human, mouse, and bovine Integrin alpha 6/CD49f. Recognizes an epitope in the extracellular domain of the Integrin alpha 6 subunit. |
| 使用方法 | Flow Cytometry: 2.5 µg/106cells Immunohistochemistry: Sonnenberg, A. et al. (1986) J. Histochem. Cytochem. 34:1037. Blockade of Receptor-ligand Interaction: Sonnenberg, A. et al. (1986) J. Histochem. Cytochem. 34:1037. Knapp, W.B. et al. Eds. (1989) Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York. Aumailley, M.R. et al. (1990) Exp. Cell Res. 188:55. |
| 来源 | Monoclonal Rat IgG2A Clone # GoH3 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3655 (Human); 16403 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. RANK signaling blockade reduces breast cancer recurrence by inducing tumor cell differentiation | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse mammary tumor cells |
| 内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
| 生物活性 | Human, Mouse, Bovine |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | The Integrin alpha 6 subunit, also known as CD49f and VLA-6 alpha subunit, forms a heterodimer with Integrin beta 1 (CD29) or beta 4 (CD104) subunits and recognizes laminin as a ligand. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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