| 货号 | MAB3438-SP |
| 别名 | carboxytripeptidase; Dipeptidyl aminopeptidase II; dipeptidyl arylamidase II; dipeptidyl peptidase 2; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; dipeptidylpeptidase 7; dipeptidyl-peptidase 7; dipeptidyl-peptidase II; DPP II; DPP2; DPP7; DPPII; EC 3.4.14.2; QPP; Quiescent cell proline dipeptidase | 全称 | Dipeptidyl-peptidase II |
| 反应种属 | Human |
| 应用 | Neutralization |
| 目标/特异性 | Detects human DPPII/QPP/DPP7 in direct ELISAs. |
| 使用方法 | Neutralization: Measured by its ability to neutralize Recombinant Human DPPII/QPP/DPP7 (0.1 µg/mL, Catalog # 3438-SE) cleavage of the fluorogenic peptide substrate KP-AMC (10 µM). The Neutralization Dose (ND50) is typically 0.12 µg/mL. |
| 来源 | Monoclonal Rat IgG2A Clone # 398011 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 29952 (Human); 83768 (Mouse); 83799 (Rat) |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human DPPII/QPP/DPP7 Gly22-Leu492 Accession # ABM85563 |
| 内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | As a serine exopeptidase that releases Xaa-Pro dipeptides from the N-terminus of proteins and peptides, DPPII/QPPDPP7 shares some substrate and cleavage specificity with the members of the DPPIV family. These enzymes have high potential for drug discovery. However, structurally DPPII is not a member of the DPPIV family, but belongs to a family that contains lysosomal Pro-X carboxypeptidase/prolylcarboxypeptidase/PRCP and thymus-specific serine peptidase/PRSS16. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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